Chloride → N-[2-(6-bromo-2-pyridinyl)-4-methylphenyl]-2,2-dimethylpropanamide

HRID 1570219Notes

Reaction equation

HRID 1570219 reaction equation
[B:15]([OH:16])([OH:17])[c:18]1[c:19]([NH:25][C:26]([C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[cH:20][cH:21][c:22]([CH3:24])[cH:23]1.[Br:1][c:2]1[n:3][c:4]([Br:8])[cH:5][cH:6][cH:7]1.[C:32](=[O:33])([OH:34])[O-:35].[CH2:9]([CH2:10][O:11][CH3:12])[O:13][CH3:14].[CH3:38][CH2:39][O:40][C:41](=[O:42])[CH3:43].[Cl-:44].[Cl-:45].[Na+:36].[OH2:37].[Pd+2:84].[c:46]1([P:47]([c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[cH:60][cH:61][cH:62][cH:63][cH:64]1.[c:65]1([P:66]([c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)[c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)[cH:79][cH:80][cH:81][cH:82][cH:83]1>>[c:2]1(-[c:18]2[c:19]([NH:25][C:26]([C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[cH:20][cH:21][c:22]([CH3:24])[cH:23]2)[n:3][c:4]([Br:8])[cH:5][cH:6][cH:7]1

Participants

11

Reactant 10

HCID 312Chloride2×HCID 769Bicarbonate IonHCID 923Sodium ionHCID 962WaterHCID 80711,2-DimethoxyethaneHCID 8857Ethyl AcetateHCID 11776Triphenylphosphine2×HCID 122742,6-DibromopyridineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 19045057N-(2-borono-4-methylphenyl)-2,2-dimethylpropanamide

Product 1

HCID 19047053N-[2-(6-bromo-2-pyridinyl)-4-methylphenyl]-2,2-dimethylpropanamide

Sources & evidence

ORD record
ord-b65ca9b7590c420eb49a1861bb2a23ae
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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