Acetate → Tert-butyl 2-[[5-cyano-2-(3-ethoxy-3-oxoprop-1-enyl)phenoxy]methyl]pyrrolidine-1-carboxylate

HRID 1571278Notes

Reaction equation

HRID 1571278 reaction equation
[C:24]([CH:25]=[CH2:26])(=[O:27])[O:28][CH2:29][CH3:30].[C:49]([O-:50])(=[O:51])[CH3:52].[C:54]([O-:55])(=[O:56])[CH3:57].[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[CH3:38][CH2:39][O:40][C:41](=[O:42])[CH3:43].[I:1][c:2]1[c:3]([O:10][CH2:11][CH:12]2[N:13]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:14][CH2:15][CH2:16]2)[cH:4][c:5]([C:6]#[N:7])[cH:8][cH:9]1.[O:44]=[CH:45][N:46]([CH3:47])[CH3:48].[Pd+2:53]>>[c:2]1([CH:26]=[CH:25][C:24](=[O:27])[O:28][CH2:29][CH3:30])[c:3]([O:10][CH2:11][CH:12]2[N:13]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:14][CH2:15][CH2:16]2)[cH:4][c:5]([C:6]#[N:7])[cH:8][cH:9]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 6228DimethylformamideHCID 8471TriethylamineHCID 8821Ethyl AcrylateHCID 8857Ethyl AcetateHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 69924446HCID 69924446, compound

Product 1

HCID 69923032Tert-butyl 2-[[5-cyano-2-(3-ethoxy-3-oxoprop-1-enyl)phenoxy]methyl]pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-64a9544e4f1245f583ad3d437604526a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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