HRID1571685

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8471

Triethylamine

C6H15N

HCID11776

Triphenylphosphine

C18H15P

2 次

HCID14284

N,N-Dimethylpyridin-4-amine

C7H10N2

HCID24290

未命名化合物

HCID66111

Trimethylsilylacetylene

C5H10Si

HCID59129194

未命名化合物

PRODUCTS

生成物

结构：COC(=O)C1(c2ccc(N)c(C#C[Si](C)(C)C)c2)CC1

HCID59129467

Cyclopropanecarboxylic acid, 1-[4-amino-3-[2-(trimethylsilyl)ethynyl]phenyl]-, methyl ester

C16H21NO2Si

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2081a94c64cd4c6384a125dab6fbedaa
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (1/10)

反应 SMILES

[C:16](#[CH:17])[Si:18]([CH3:19])([CH3:20])[CH3:21].[CH3:22][CH2:23][N:24]([CH2:25][CH3:26])[CH2:27][CH3:28].[CH3:29][N:30]([c:31]1[cH:32][cH:33][n:34][cH:35][cH:36]1)[CH3:37].[NH2:1][c:2]1[c:3]([Br:15])[cH:4][c:5]([C:8]2([C:11](=[O:12])[O:13][CH3:14])[CH2:9][CH2:10]2)[cH:6][cH:7]1.[Pd:38]([Cl:39])[Cl:40].[c:41]1([P:42]([c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[cH:55][cH:56][cH:57][cH:58][cH:59]1.[c:60]1([P:61]([c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)[c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)[cH:74][cH:75][cH:76][cH:77][cH:78]1>>[NH2:1][c:2]1[c:3]([C:17]#[C:16][Si:18]([CH3:19])([CH3:20])[CH3:21])[cH:4][c:5]([C:8]2([C:11](=[O:12])[O:13][CH3:14])[CH2:9][CH2:10]2)[cH:6][cH:7]1