Triethylamine → Cyclopropanecarboxylic acid, 1-[4-amino-3-[2-(trimethylsilyl)ethynyl]phenyl]-, methyl ester
Reaction equation
[C:16](#[CH:17])[Si:18]([CH3:19])([CH3:20])[CH3:21].[CH3:22][CH2:23][N:24]([CH2:25][CH3:26])[CH2:27][CH3:28].[CH3:29][N:30]([c:31]1[cH:32][cH:33][n:34][cH:35][cH:36]1)[CH3:37].[NH2:1][c:2]1[c:3]([Br:15])[cH:4][c:5]([C:8]2([C:11](=[O:12])[O:13][CH3:14])[CH2:9][CH2:10]2)[cH:6][cH:7]1.[Pd:38]([Cl:39])[Cl:40].[c:41]1([P:42]([c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[cH:55][cH:56][cH:57][cH:58][cH:59]1.[c:60]1([P:61]([c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)[c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)[cH:74][cH:75][cH:76][cH:77][cH:78]1>>[NH2:1][c:2]1[c:3]([C:17]#[C:16][Si:18]([CH3:19])([CH3:20])[CH3:21])[cH:4][c:5]([C:8]2([C:11](=[O:12])[O:13][CH3:14])[CH2:9][CH2:10]2)[cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-2081a94c64cd4c6384a125dab6fbedaa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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