Hydrochloric Acid → N-(3-fluoro-4-(2-iodothieno[3,2-b]pyridin-7-yloxy)phenyl)-2-(4-fluorophenyl)-3-oxo-2,3-dihydropyridazine-4-carboxamide

HRID 1571900Notes

Reaction equation

HRID 1571900 reaction equation
[CH2:38]([N:39]=[C:40]=[N:41][CH2:42][CH2:43][CH2:44][N:45]([CH3:46])[CH3:47])[CH3:48].[CH2:59]([N:60]([CH:61]([CH3:62])[CH3:63])[CH:64]([CH3:65])[CH3:66])[CH3:67].[ClH:37].[F:1][c:2]1[cH:3][c:4]([NH2:5])[cH:6][cH:7][c:8]1[O:9][c:10]1[c:11]2[c:12]([n:13][cH:14][cH:15]1)[cH:16][c:17]([I:19])[s:18]2.[F:20][c:21]1[cH:22][cH:23][c:24](-[n:27]2[n:28][cH:29][cH:30][c:31]([C:34](=[O:35])[OH:36])[c:32]2=[O:33])[cH:25][cH:26]1.[O:68]=[CH:69][N:70]([CH3:71])[CH3:72].[n:49]1([OH:50])[c:51]2[cH:52][cH:53][cH:54][cH:55][c:56]2[n:57][n:58]1>>[F:1][c:2]1[cH:3][c:4]([NH:5][C:34]([c:31]2[cH:30][cH:29][n:28][n:27](-[c:24]3[cH:23][cH:22][c:21]([F:20])[cH:26][cH:25]3)[c:32]2=[O:33])=[O:35])[cH:6][cH:7][c:8]1[O:9][c:10]1[c:11]2[c:12]([n:13][cH:14][cH:15]1)[cH:16][c:17]([I:19])[s:18]2

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 757711-HydroxybenzotriazoleHCID 81531DiisopropylethylamineHCID 584749503-Fluoro-4-((2-iodothieno[3,2-b]pyridin-7-yl)oxy)anilineHCID 667671712-(4-Fluorophenyl)-3-oxo-2,3-dihydropyridazine-4-carboxylic acid

Product 1

HCID 67348506N-(3-fluoro-4-(2-iodothieno[3,2-b]pyridin-7-yloxy)phenyl)-2-(4-fluorophenyl)-3-oxo-2,3-dihydropyridazine-4-carboxamide

Sources & evidence

ORD record
ord-7e96a5306208488880326f80a09a7121
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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