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HRID15767

反应详情

EQUATION

反应方程式

HRID 15767 的结构方程式

REACTANTS

反应物

6
结构：c1cn[nH]c1
HCID1048

Pyrazole

C3H4N2

结构：O=S(=O)(Cl)c1ccc(F)cc1
HCID9588

Benzenesulfonyl chloride, 4-fluoro-

C6H4ClFO2S

结构：NN.O
HCID24654

Hydrazine hydrate (1:1)

H6N2O

结构：COC(OC)N(C)C
HCID78373

Methanamine, 1,1-dimethoxy-N,N-dimethyl-

C5H13NO2

结构：CC[C@@H]1CC2(C[C@H](CC)N1)OCCO2
HCID59342374

未命名化合物

结构：CCC1CC(=O)CC(CC)N1S(=O)(=O)c1ccc(F)cc1
HCID68501988

未命名化合物

PRODUCTS

生成物

1
结构：CC[C@@H]1Cc2[nH]ncc2[C@H](CC)N1S(=O)(=O)c1ccc(F)cc1
HCID68499313

未命名化合物

PROCEDURE

实验过程

Prepared by treatment of 2,6-diethyl-1-(4-fluorophenylsulfonyl)piperidin-4-one, which was prepared by sulfonylation of compound 126 using 4-fluorobenzenesulfonyl chloride followed by deprotection as shown in Example 17, with DMF-DMA followed by pyrazole formation using hydrazine hydrate as shown in Example 15.