Acetate → Ethyl 3-(pyrimidin-5-yl)prop-2-enoate

HRID 157885Notes

Reaction equation

HRID 157885 reaction equation
[Br:1][c:2]1[cH:3][n:4][cH:5][n:6][cH:7]1.[C:41]([O-:42])(=[O:43])[CH3:44].[C:46]([O-:47])(=[O:48])[CH3:49].[C:8]([CH:9]=[CH2:10])(=[O:11])[O:12][CH2:13][CH3:14].[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[OH2:50].[Pd+2:45].[c:15]1([P:16]([c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[cH:29][cH:30][cH:31][cH:32][cH:33]1>>[c:2]1([CH:10]=[CH:9][C:8](=[O:11])[O:12][CH2:13][CH3:14])[cH:3][n:4][cH:5][n:6][cH:7]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 962WaterHCID 8471TriethylamineHCID 8821Ethyl AcrylateHCID 11776TriphenylphosphineHCID 783445-BromopyrimidineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

Product 1

HCID 53438539Ethyl 3-(pyrimidin-5-yl)prop-2-enoate

Sources & evidence

ORD record
ord-fd926ff484ec4b39ac454530401500bc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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