Triphenylphosphine → HCID 59258895, compound

HRID 160812Notes

Reaction equation

HRID 160812 reaction equation
[CH2:78]1[O:79][CH2:80][CH2:81][O:82][CH2:83]1.[CH:1]([N:2]([CH:3]([CH3:4])[CH3:5])[CH2:6][CH3:7])([CH3:8])[CH3:9].[Cu:75]([I:76])[I:77].[NH2:10][c:11]1[n:12][c:13]([CH3:27])[c:14]2[c:15]([n:16]1)[n:17]([CH:23]1[CH2:24][CH2:25][CH2:26]1)[c:18](=[O:22])[c:19]([Br:21])[cH:20]2.[Pd:34]([Cl:35])[Cl:36].[Si:28]([CH3:29])([CH3:30])([CH3:31])[C:32]#[CH:33].[c:37]1([P:38]([c:39]2[cH:40][cH:41][cH:42][cH:43][cH:44]2)[c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)[cH:51][cH:52][cH:53][cH:54][cH:55]1.[c:56]1([P:57]([c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)[cH:70][cH:71][cH:72][cH:73][cH:74]1>>[NH2:10][c:11]1[n:12][c:13]([CH3:27])[c:14]2[c:15]([n:16]1)[n:17]([CH:23]1[CH2:24][CH2:25][CH2:26]1)[c:18](=[O:22])[c:19]([C:33]#[C:32][Si:28]([CH3:29])([CH3:30])[CH3:31])[cH:20]2

Participants

8

Reactant 7

HCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 312751,4-DioxaneHCID 66111TrimethylsilylacetyleneHCID 81531DiisopropylethylamineHCID 83717Copper iodideHCID 67240606HCID 67240606, compound

Product 1

HCID 59258895HCID 59258895, compound

Sources & evidence

ORD record
ord-e33fced8d9d2452a992925bd762d59e7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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