huagongshe.com
HRID1648426

反应详情

EQUATION

反应方程式

HRID 1648426 的结构方程式

REACTANTS

反应物

4
结构：CC(=O)O
HCID176

Acetic Acid

C2H4O2

结构：O.O.O.O.O.O=S(=O)([O-])[O-].[Cu+2]
HCID24463

Copper(II) sulfate, pentahydrate

H10CuO9S

结构：Cl.NO
HCID443297

未命名化合物

结构：C#CC(C)N1C(=O)c2ccccc2C1=O
HCID603633

2-(BUT-3-YN-2-YL)ISOINDOLINE-1,3-DIONE

C12H9NO2

PRODUCTS

生成物

1
结构：C#CC([CH2-])N1C(=O)c2ccccc2C1=O.[Cu+]
HCID86748809

未命名化合物

收率 91%

AUXILIARIES

试剂、催化剂与溶剂

3
结构：CC(C)=O
溶剂HCID180

Acetone

C3H6O

2 次

结构：O
溶剂HCID962

Water

H2O

2 次

结构：[NH4+].[OH-]
溶剂HCID14923

Ammonium hydroxide

H5NO

PROCEDURE

实验过程

To a solution of copper sulfate pentahydrate (0.098 mol), under nitrogen, in 100 ml of 28% ammonium hydroxide and water (315 ml), hydroxylamine hydrochloride (0.175 mol) is added. After the change in color (blue to green) 62.5 ml of acetone is added. Immediately afterwards, a solution of 2-phthalimido-3-butyne (0.0875 mol) in 280 ml of acetone is added. After 5 minutes of vigorous stirring, a solution of 30.8 ml of glacial acetic acid in 455 ml of water is added. The yellow precipitate is filtered off, washed and dried in vacuo to yield the title product (yield 91%).

WORKUP

后处理

  1. filtrationThe yellow precipitate is filtered off
  2. washwashed
  3. customdried in vacuo