Nitromethane → HCID 12021882, compound

HRID 1656889Notes

Reaction equation

HRID 1656889 reaction equation
[N+:1]([CH3:4])([O-:3])=[O:2].C(NCC)C.[N:10]1[CH:15]=[CH:14][CH:13]=[C:12]([CH:16]=[O:17])[CH:11]=1>C(O)C>[N:10]1[CH:15]=[CH:14][CH:13]=[C:12]([CH:16]([OH:17])[CH2:4][N+:1]([O-:3])=[O:2])[CH:11]=1

Participants

5

Reactant 3

HCID 6375NitromethaneHCID 8021DiethylamineHCID 103713-Pyridinecarboxaldehyde

Product 1

HCID 12021882HCID 12021882, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
0 °C

Procedure

To a cooled stirring solution of 15 grams (0.25 mol) nitromethane and 0.35 gram (0.005 mol) diethylamine in 26 milliliters of ethanol was added dropwise 10 grams (0.093 mol) 3-pyridine carboxaldehyde. The reaction was stirred for 3 hours at 0° C. then warmed to ambient temperature. Concentration yielded crude 1-(3-pyridyl)-2-nitroethanol.

Workup

  1. temperaturethen warmed to ambient temperature
  2. concentrationConcentration

Sources & evidence

ORD record
ord-cd95e3b067e040b1ad052ccf62be70ef
Source dataset
uspto-grants-1993_10
Patent number
US05256626

Reaction notes

Loading…