O-Cresol → 4-Methylphenyl phosphorodichloridate

HRID 1658656Notes

Reaction equation

HRID 1658656 reaction equation
[P:1]([Cl:5])(Cl)([Cl:3])=[O:2].[CH3:6]N.[C:8]1(C)[C:13]([OH:14])=[CH:12][CH:11]=[CH:10][CH:9]=1>>[P:1]([Cl:5])([Cl:3])(=[O:2])[O:14][C:13]1[CH:8]=[CH:9][C:10]([CH3:6])=[CH:11][CH:12]=1

Participants

4

Reactant 3

HCID 335O-CresolHCID 6329MethylamineHCID 24813Phosphorus oxychloride

Product 1

HCID 2489054-Methylphenyl phosphorodichloridate

Procedure

To a mixture of 225 g. phosphoryl chloride and methylamine there is added 109 g. cresol over a period of 2 hours at a temperature of 105°C. The temperature is held at 105°-110°C. for two hours to afford cresyl phosphorodichloridate.

Workup

  1. additionTo a mixture of 225 g

Sources & evidence

ORD record
ord-5f7e99a2500f40eb89c7d01d3d293f9a
Source dataset
uspto-grants-1976_06
Patent number
US03965220

Reaction notes

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