HRID1676939

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：NS(=O)(=O)c1cc(-c2nn[nH]n2)c(NCc2cccs2)cc1Cl

HCID2273

Azosemide

C12H11ClN6O2S2

HCID5238

Sodium Iodide

INa

HCID8471

Triethylamine

C6H15N

HCID137983

[(Chloromethoxy)methyl]benzene

C8H9ClO

PRODUCTS

生成物

结构：NS(=O)(=O)c1cc(-c2nnnn2COCc2ccccc2)c(NCc2cccs2)cc1Cl

HCID60208427

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

Azosemide can be reacted with benzyl chloromethyl ether, triethylamine and sodium iodide in DMF to yield 5-[1-(benzyloxymethyl)-1H-tetrazol-5-yl]-2-chloro-4-[(2-thienylmethyl)amino]benzenesulfonamide.