Iodoethane → HCID 55220820, compound

HRID 1686388Notes

Reaction equation

HRID 1686388 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([SH:9])[CH:5]=[CH:6][C:7]=1[F:8].[CH2:10](I)[CH3:11].C(=O)([O-])[O-].[K+].[K+]>CN(C=O)C>[CH2:10]([S:9][C:4]1[CH:5]=[CH:6][C:7]([F:8])=[C:2]([F:1])[CH:3]=1)[CH3:11]

Participants

5

Reactant 3

HCID 6340IodoethaneHCID 11430Potassium CarbonateHCID 27783783,4-Difluorobenzenethiol

Product 1

HCID 55220820HCID 55220820, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A solution of 3,4-difluorothiophenol (3 g), ethyl iodide (1.6 ml), potassium carbonate (2.64 g) and DMF (40 ml) were charged to a flask and stirred for 2 h. The solution was partitioned between ethyl acetate and water. The organic extracts were dried (MgSO4) and evaporated under reduced pressure to give the subtitle compound (3.84 g).

Workup

  1. customThe solution was partitioned between ethyl acetate and water
  2. dry with materialThe organic extracts were dried (MgSO4)
  3. customevaporated under reduced pressure

Sources & evidence

ORD record
ord-ee21a092a95d41ff9781ec7dabf02d61
Source dataset
uspto-grants-2012_04
Patent number
US08148572B2

Reaction notes

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