1,2-Dimethoxyethane → 1-Phenyl-2-(trimethylsilyl)acetylene

HRID 169849Notes

Reaction equation

HRID 169849 reaction equation
[CH3:14][CH2:15][N:16]([CH2:17][CH3:18])[CH2:19][CH3:20].[CH3:21][O:22][CH2:23][CH2:24][O:25][CH3:26].[CH3:8][Si:9]([CH3:10])([CH3:11])[C:12]#[CH:13].[Cu:68][I:69].[I:1][c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1.[Pd:27]([Cl:28])[Cl:29].[c:30]1([P:31]([c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[cH:44][cH:45][cH:46][cH:47][cH:48]1.[c:49]1([P:50]([c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)[c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)[cH:63][cH:64][cH:65][cH:66][cH:67]1>>[c:2]1([C:13]#[C:12][Si:9]([CH3:8])([CH3:10])[CH3:11])[cH:3][cH:4][cH:5][cH:6][cH:7]1

Participants

8

Reactant 7

HCID 80711,2-DimethoxyethaneHCID 8471TriethylamineHCID 11575IodobenzeneHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66111Trimethylsilylacetylene

Product 1

HCID 1374641-Phenyl-2-(trimethylsilyl)acetylene

Sources & evidence

ORD record
ord-7e1a31f1291b4a1f8db6cf61056e8c98
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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