Triethylamine → 4-Bromo-5-fluoro-2-[2-(trimethylsilyl)ethynyl]benzenamine
Reaction equation
[Br:7][c:8]1[cH:9][c:10]([I:16])[c:11]([NH2:12])[cH:13][c:14]1[F:15].[CH3:1][Si:2]([CH3:3])([CH3:4])[C:5]#[CH:6].[CH3:60][CH2:61][N:62]([CH2:63][CH3:64])[CH2:65][CH3:66].[Cu:58][I:59].[Pd:17]([Cl:18])[Cl:19].[c:20]1([P:21]([c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[cH:34][cH:35][cH:36][cH:37][cH:38]1.[c:39]1([P:40]([c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[cH:53][cH:54][cH:55][cH:56][cH:57]1>>[CH3:1][Si:2]([CH3:3])([CH3:4])[C:5]#[C:6][c:10]1[cH:9][c:8]([Br:7])[c:14]([F:15])[cH:13][c:11]1[NH2:12]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-22c163f7b295400cbeb8dfdc3e22d54a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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