Tetrahydrofuran → HCID 59424500, compound

HRID 175791Notes

Reaction equation

HRID 175791 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[n:5][cH:6][cH:7][c:8]([O:11][c:12]3[c:13]([F:21])[cH:14][c:15]([N+:18](=[O:19])[O-:20])[cH:16][cH:17]3)[c:9]2[s:10]1.[CH2:22]([C:23]#[CH:24])[N:25]1[CH2:26][CH2:27][O:28][CH2:29][CH2:30]1.[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[Cu:43][I:44].[Pd:45]([Cl:46])[Cl:47].[c:48]1([P:49]([c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[cH:62][cH:63][cH:64][cH:65][cH:66]1.[c:67]1([P:68]([c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)[c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)[cH:81][cH:82][cH:83][cH:84][cH:85]1>>[c:2]1([C:24]#[C:23][CH2:22][N:25]2[CH2:26][CH2:27][O:28][CH2:29][CH2:30]2)[cH:3][c:4]2[n:5][cH:6][cH:7][c:8]([O:11][c:12]3[c:13]([F:21])[cH:14][c:15]([N+:18](=[O:19])[O-:20])[cH:16][cH:17]3)[c:9]2[s:10]1

Participants

8

Reactant 7

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 4129414-(2-Propyn-1-yl)morpholineHCID 594245212-Bromo-7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine

Product 1

HCID 59424500HCID 59424500, compound

Sources & evidence

ORD record
ord-ae124edbb3804181a358b7830e7ea77e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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