Methanol → HCID 58486960, compound

HRID 175902Notes

Reaction equation

HRID 175902 reaction equation
[CH3:41][N:42]([c:43]1[cH:44][cH:45][n:46][cH:47][cH:48]1)[CH3:49].[CH3:58][OH:59].[CH:32]([N:33]([CH2:34][CH3:35])[CH:36]([CH3:37])[CH3:38])([CH3:39])[CH3:40].[Cl:50][CH2:51][Cl:52].[F:12][C:13]([c:14]1[c:15](-[c:23]2[cH:24][cH:25][c:26]([NH2:29])[n:27][cH:28]2)[cH:16][c:17]2[c:18]([n:19][s:20][n:21]2)[cH:22]1)([F:30])[F:31].[F:1][c:2]1[c:3]([C:4](=[O:5])[Cl:6])[c:7]([F:11])[cH:8][cH:9][cH:10]1.[Li+:60].[O:53]1[CH2:54][CH2:55][CH2:56][CH2:57]1.[OH-:61]>>[F:1][c:2]1[c:3]([C:4](=[O:5])[NH:29][c:26]2[cH:25][cH:24][c:23](-[c:15]3[c:14]([C:13]([F:12])([F:30])[F:31])[cH:22][c:18]4[c:17]([cH:16]3)[n:21][s:20][n:19]4)[cH:28][n:27]2)[c:7]([F:11])[cH:8][cH:9][cH:10]1

Participants

10

Reactant 9

HCID 887MethanolHCID 961HydroxideHCID 6344DichloromethaneHCID 8028TetrahydrofuranHCID 142844-(Dimethylamino)pyridineHCID 28486Lithium ionHCID 81531DiisopropylethylamineHCID 874382,6-Difluorobenzoyl chlorideHCID 58487437HCID 58487437, compound

Product 1

HCID 58486960HCID 58486960, compound

Sources & evidence

ORD record
ord-33f669f5d03d40d9b1069b3f2374eff6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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