1,2-Dichloroethane → 1-Benzylpiperidine-4-carboxylic acid

HRID 183092Notes

Reaction equation

HRID 183092 reaction equation
[C:18]([O:19][BH-:20]([O:21][C:22](=[O:23])[CH3:24])[O:25][C:26](=[O:27])[CH3:28])(=[O:29])[CH3:30].[CH3:38][CH2:39][N:40]([CH2:41][CH3:42])[CH2:43][CH3:44].[CH:10](=[O:11])[c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1.[Cl:34][CH2:35][CH2:36][Cl:37].[ClH:32].[NH:1]1[CH2:2][CH2:3][CH:4]([C:5](=[O:6])[OH:7])[CH2:8][CH2:9]1.[Na+:31].[OH2:33]>>[N:1]1([CH2:10][c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[CH2:2][CH2:3][CH:4]([C:5](=[O:6])[OH:7])[CH2:8][CH2:9]1

Participants

9

Reactant 8

HCID 111,2-DichloroethaneHCID 240BenzaldehydeHCID 313Hydrochloric AcidHCID 923Sodium ionHCID 962WaterHCID 37734-Piperidinecarboxylic acidHCID 8471TriethylamineHCID 2724942Triacetoxyborohydride

Product 1

HCID 47149831-Benzylpiperidine-4-carboxylic acid

Sources & evidence

ORD record
ord-7d238c4e3c634cb09ff488c98345d7aa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…