Dimethylformamide → N-(5-{[2-(acetylamino)[1,3]thiazolo[5,4-b]pyridin-5-yl]oxy}-2-chlorophenyl)-2-chloro-3-(1-cyano-1-methylethyl)benzamide
Reaction equation
[CH3:49][N:50]([CH3:51])[CH:52]=[O:53].[CH3:54][CH2:55][O:56][C:57](=[O:58])[CH3:59].[Cl:16][C:17]([C:18]([Cl:19])=[O:20])=[O:21].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][cH:9][c:10]1[C:11]([CH3:12])([CH3:13])[C:14]#[N:15].[NH2:22][c:23]1[cH:24][c:25]([O:26][c:27]2[cH:28][cH:29][c:30]3[c:31]([n:32]2)[s:33][c:34]([NH:36][C:37]([CH3:38])=[O:39])[n:35]3)[cH:40][cH:41][c:42]1[Cl:43].[O:44]1[CH2:45][CH2:46][CH2:47][CH2:48]1>>[Cl:1][c:2]1[c:3]([C:4](=[O:6])[NH:22][c:23]2[cH:24][c:25]([O:26][c:27]3[cH:28][cH:29][c:30]4[c:31]([n:32]3)[s:33][c:34]([NH:36][C:37]([CH3:38])=[O:39])[n:35]4)[cH:40][cH:41][c:42]2[Cl:43])[cH:7][cH:8][cH:9][c:10]1[C:11]([CH3:12])([CH3:13])[C:14]#[N:15]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-fc6bc78fba3c4e0e846a19d4c2e3cc27
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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