2-Bromopyridine → HCID 66598649, compound

HRID 185396Notes

Reaction equation

HRID 185396 reaction equation
[Br:1][c:2]1[cH:3][cH:4][cH:5][cH:6][n:7]1.[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35].[Cl:8][c:9]1[cH:10][cH:11][c:12]([N:15]([C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[C:23]([CH2:24][CH2:25][C:26]#[CH:27])=[O:28])[cH:13][cH:14]1.[Cu:36][I:37].[Pd:38]([Cl:39])[Cl:40].[c:41]1([P:42]([c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[cH:55][cH:56][cH:57][cH:58][cH:59]1.[c:60]1([P:61]([c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)[c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)[cH:74][cH:75][cH:76][cH:77][cH:78]1>>[c:2]1([C:27]#[C:26][CH2:25][CH2:24][C:23]([N:15]([c:12]2[cH:11][cH:10][c:9]([Cl:8])[cH:14][cH:13]2)[C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])=[O:28])[cH:3][cH:4][cH:5][cH:6][n:7]1

Participants

7

Reactant 6

HCID 79732-BromopyridineHCID 8471TriethylamineHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 86630254HCID 86630254, compound

Product 1

HCID 66598649HCID 66598649, compound

Sources & evidence

ORD record
ord-25b13de151794d2da2013965aba8196f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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