Acetic Acid → HCID 367454, compound

HRID 1857370Notes

Reaction equation

HRID 1857370 reaction equation
[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=O)=[CH:6][CH:5]=1)([O-:3])=[O:2].[C:12]([CH2:15][C:16](=[O:18])[CH3:17])(=[O:14])[CH3:13].N1CCCCC1.C(O)(=O)C>C(O)(C)C>[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=[C:15]([C:16](=[O:18])[CH3:17])[C:12](=[O:14])[CH3:13])=[CH:6][CH:5]=1)([O-:3])=[O:2]

Participants

6

Reactant 4

HCID 176Acetic AcidHCID 5414-NitrobenzaldehydeHCID 8082PiperidineHCID 31261Acetylacetone

Product 1

HCID 367454HCID 367454, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

30.2 g (0.2 mol) of 4-nitrobenzaldehyde and 30.0 g (0.3 mol) of acetylacetone are dissolved in 200 ml of isopropanol and treated with 1.2 ml of piperidine and 1 ml of glacial acetic acid. The mixture is warmed in a water bath until a clear solution is formed and then stirred at RT for 4 h. The product precipitates and is filtered off with suction.

Workup

  1. temperatureThe mixture is warmed in a water bath until a clear solution
  2. customis formed
  3. customThe product precipitates
  4. filtrationis filtered off with suction

Sources & evidence

ORD record
ord-a570f78df2fc4530abca2a69c8ff7e55
Source dataset
uspto-grants-2000_11
Patent number
US06147087

Reaction notes

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