反应详情

A solution of 0.5 g of compound 6, 0.8 g of K2CO3 and 0.3 g of ethyliodide was stirred in 20 ml of N-methyl-pyrrolidinone for 4 h at 70° C. After cooling to room temperature, the reaction mixture was poured into 200 ml of water and this mixture was extracted with diethyl ether. After drying over magnesium sulfate, the solvent was evaporated and the compound crystallized from methanol, M.p. 124-127° C.

1. extractionthis mixture was extracted with diethyl ether
2. dry with materialAfter drying over magnesium sulfate
3. customthe solvent was evaporated
4. customthe compound crystallized from methanol, M.p. 124-127° C.