反应详情

In the same manner as in Example 18-4 and using 1-ethyl-3-methyl-1H-pyrazole-4-carboxylic acid (198 mg, 1.28 mmol), tetrahydrofuran (7 mL), oxalyl chloride (169 μL, 1.94 mmol), N-[6-(3-aminophenoxy)[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide (200 mg, 0.646 mmol), N,N-dimethylformamide (1 drop) and N,N-dimethylacetamide (3 mL) as starting materials, the title compound (230 mg, 80%) was obtained as a white solid.