Dimethylformamide → HCID 86633441, compound

HRID 1881187Notes

Reaction equation

HRID 1881187 reaction equation
[CH2:1]([O:3][C:4]1[C:5]([OH:18])=[C:6]([N+:15]([O-:17])=[O:16])[C:7]([N+:12]([O-:14])=[O:13])=[C:8]([CH:11]=1)[CH:9]=[O:10])[CH3:2].CN(C)C=O.C([O-])([O-])=O.[K+].[K+].[CH2:30](Br)[CH3:31]>C(OCC)C>[CH2:30]([O:18][C:5]1[C:4]([O:3][CH2:1][CH3:2])=[CH:11][C:8]([CH:9]=[O:10])=[C:7]([N+:12]([O-:14])=[O:13])[C:6]=1[N+:15]([O-:17])=[O:16])[CH3:31]

Participants

6

Reactant 4

HCID 6228DimethylformamideHCID 6332Ethyl BromideHCID 11430Potassium CarbonateHCID 86633440HCID 86633440, compound

Product 1

HCID 86633441HCID 86633441, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

5-Ethoxy-4-hydroxy-2,3-dinitro-benzaldehyde (3.77 g), N,N-dimethylformamide (35 ml), K2CO3 (3.877 g) and ethyl bromide (50 ml) were refluxed 24 hours. To the reaction solution was added diethyl ether (100 ml) and then it was washed with water and 1M sodium hydroxide. The solution was dried and evaporated.

Workup

  1. washit was washed with water and 1M sodium hydroxide
  2. customThe solution was dried
  3. customevaporated

Sources & evidence

ORD record
ord-360da99a33264717ae57c90d3191fd1f
Source dataset
uspto-grants-2012_11
Patent number
US08318785B2

Reaction notes

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