反应详情

To S-(2-trimethylsilylethyl)-3-fluoro-5-phenylthiophenol (2.4 g) in DMF (50 mL) was added Bu4NF (16 mL of a 1M THF solution). After 90 min., EtOAc was added and this solution was washed with 1N HCl, H2O and brine. Concentration and chromatography (silica gel; hexane/EtOAc (9:1)) provided the title compound as a liquid.

1. washthis solution was washed with 1N HCl, H2O and brine
2. concentrationConcentration and chromatography (silica gel; hexane/EtOAc (9:1))