Hydrochloric Acid → tert-butyl 2-[(5-chloro-1H-pyrrolo[2,3-b]pyridine-2-carbonyl)amino]-3-(4-fluorophenyl)propanoate
Reaction equation
[C:15]([CH3:16])([CH3:17])([CH3:18])[O:19][C:20]([CH:21]([CH2:22][c:23]1[cH:24][cH:25][c:26]([F:29])[cH:27][cH:28]1)[NH2:30])=[O:31].[CH3:51][CH2:52][N:53]=[C:54]=[N:55][CH2:56][CH2:57][CH2:58][N:59]([CH3:60])[CH3:61].[CH:42]([N:43]([CH2:44][CH3:45])[CH:46]([CH3:47])[CH3:48])([CH3:49])[CH3:50].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[nH:8][c:9]([C:11](=[O:12])[OH:13])[cH:10]2.[ClH:14].[O:62]=[CH:63][N:64]([CH3:65])[CH3:66].[OH:32][n:33]1[c:34]2[c:35]([cH:36][cH:37][cH:38][cH:39]2)[n:40][n:41]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[nH:8][c:9]([C:11](=[O:13])[NH:30][CH:21]([C:20]([O:19][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:31])[CH2:22][c:23]1[cH:24][cH:25][c:26]([F:29])[cH:27][cH:28]1)[cH:10]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-58628d84763c4586beca533934cfcd6b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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