Tetrahydrofuran → 3-(1-cyano-1-methylethyl)-N-{2-methyl-5-[(2-{[(4-methylpiperazin-1-yl)acetyl]amino}-1,3-benzothiazol-6-yl)oxy]phenyl}benzamide
Reaction equation
[CH3:37][CH2:38][N:39]([CH2:40][CH3:41])[CH2:42][CH3:43].[CH3:44][N:45]1[CH2:46][CH2:47][NH:48][CH2:49][CH2:50]1.[CH3:56][CH2:57][O:58][C:59](=[O:60])[CH3:61].[Cl:1][CH2:2][C:3](=[O:4])[NH:5][c:6]1[s:7][c:8]2[c:9]([n:10]1)[cH:11][cH:12][c:13]([O:15][c:16]1[cH:17][cH:18][c:19]([CH3:36])[c:20]([NH:22][C:23]([c:24]3[cH:25][c:26]([C:30]([CH3:31])([CH3:32])[C:33]#[N:34])[cH:27][cH:28][cH:29]3)=[O:35])[cH:21]1)[cH:14]2.[O:51]1[CH2:52][CH2:53][CH2:54][CH2:55]1>>[CH2:2]([C:3](=[O:4])[NH:5][c:6]1[s:7][c:8]2[c:9]([n:10]1)[cH:11][cH:12][c:13]([O:15][c:16]1[cH:17][cH:18][c:19]([CH3:36])[c:20]([NH:22][C:23]([c:24]3[cH:25][c:26]([C:30]([CH3:31])([CH3:32])[C:33]#[N:34])[cH:27][cH:28][cH:29]3)=[O:35])[cH:21]1)[cH:14]2)[N:48]1[CH2:47][CH2:46][N:45]([CH3:44])[CH2:50][CH2:49]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-0a317701b4824fb090bb499cb30b0433
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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