Hydrochloric Acid → 3-Iodo-N-methoxy-N-methylbenzamide

HRID 199824Notes

Reaction equation

HRID 199824 reaction equation
[CH3:23][N:24]([CH3:25])[CH2:26][CH2:27][CH2:28][N:29]=[C:30]=[N:31][CH2:32][CH3:33].[CH3:35][NH:36][O:37][CH3:38].[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[ClH:22].[ClH:34].[I:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[OH:7])[cH:8][cH:9][cH:10]1.[O:46]=[CH:47][N:48]([CH3:49])[CH3:50].[OH2:21].[OH2:51].[OH:11][n:12]1[c:13]2[c:14]([cH:15][cH:16][cH:17][cH:18]2)[n:19][n:20]1>>[I:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[N:36]([CH3:35])[O:37][CH3:38])[cH:8][cH:9][cH:10]1

Participants

9

Reactant 8

HCID 313Hydrochloric Acid2×HCID 962Water2×HCID 6228DimethylformamideHCID 8471TriethylamineHCID 120603-Iodobenzoic acidHCID 14232N,O-DimethylhydroxylamineHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 757711-Hydroxybenzotriazole

Product 1

HCID 223220523-Iodo-N-methoxy-N-methylbenzamide

Sources & evidence

ORD record
ord-e0a3df88bd314c85896bf147c96e0bef
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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