Carbon Monoxide → Methyl 3-oxocyclopent-1-enecarboxylate

HRID 2002427Notes

Reaction equation

HRID 2002427 reaction equation
[CH3:1]c1ccc(S([O:2][C:3]([CH2:8][CH2:7][C:5]2=[O:6])=[CH:4]2)(=O)=O)cc1.[C-:9]#[O+:10]>>[CH3:1][O:2][C:9]([C:3]([CH2:8][CH2:7][C:5]1=[O:6])=[CH:4]1)=[O:10]

Participants

9

Reactant 3

HCID 281Carbon MonoxideHCID 887MethanolHCID 86196686(3-Oxocyclopenten-1-yl) 4-methylbenzenesulfonate

Product 1

HCID 11029917Methyl 3-oxocyclopent-1-enecarboxylate

Reagents, catalysts & solvents 5

HCID 81531DiisopropylethylamineReagentHCID 167845palladium(II) acetateCatalystHCID 611933(Pentane-1,5-diyl)bis(di-tert-butylphosphane)CatalystHCID 6342AcetonitrileSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
110 °C

Sources & evidence

ORD record
ord-e4d0c2bb4db14f19bcca225dac8d5341
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

Loading…