Ammonium Hydroxide → HCID 178433336, compound

HRID 2002632Notes

Reaction equation

HRID 2002632 reaction equation
[CH3:1][CH:2]([N:4]1[c:16]([c:9]2[CH:8]=[C:7](Br)[C:5]1=[O:6])[n:15][c:13]([NH2:14])[n:12][c:10]2[CH3:11])[CH3:3].[NH4+:17].[OH-:18]>>[CH3:1][CH:2]([N:4]1[c:16]([c:9]2[CH:8]=[C:7](C([NH2:17])=[O:18])[C:5]1=[O:6])[n:15][c:13]([NH2:14])[n:12][c:10]2[CH3:11])[CH3:3]

Participants

8

Reactant 2

HCID 14923Ammonium HydroxideHCID 57606978HCID 57606978, compound

Product 1

HCID 178433336HCID 178433336, compound

Reagents, catalysts & solvents 5

HCID 81531DiisopropylethylamineReagentHCID 167845palladium(II) acetateCatalystHCID 117064351(R)-1-[(S)-2-(Dicyclohexylphosphino)ferrocenyl]ethyli-tert-butylphosphineCatalystHCID 6342AcetonitrileSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
90 °C

Sources & evidence

ORD record
ord-018e562c942b45a7b67c1f2f4b9b7aa9
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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