1-Methyl-1H-indazole-6-boronic acid → US10308615, Example 137
Reaction equation
[CH3:1][n:2]1[c:10]([c:5]2[cH:4][n:3]1)[cH:9][c:8](B(O)[OH:11])[cH:7][cH:6]2.Br[c:12]1[cH:25][n:24][c:15]([NH:16][CH2:17][c:18]2[cH:23][n:22][cH:21][n:20][cH:19]2)[n:14][cH:13]1>>[CH3:1][n:2]1[c:10]([c:5]2[cH:4][n:3]1)[cH:9][c:8](C([c:12]3[cH:25][n:24][c:15]([NH:16][CH2:17][c:18]4[cH:23][n:22][cH:21][n:20][cH:19]4)[n:14][cH:13]3)=[O:11])[cH:7][cH:6]2Participants
7
Reactant 2
Product 1
Reagents, catalysts & solvents 4
Conditions
- Temperature
- 100 °C
Sources & evidence
- ORD record
- ord-79ca0738fde248b78ece0182016bc58f
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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