Pyrazole → HCID 178466680, compound

HRID 2003880Notes

Reaction equation

HRID 2003880 reaction equation
[CH3:1][CH2:2][O:3][c:4]1[c:10](I)[cH:9][c:8]([C:11]#[N:12])[c:6]([Cl:7])[cH:5]1.[cH:13]1[cH:17][nH:16][n:15][cH:14]1>>[CH3:1][CH2:2][O:3][c:4]1[c:10]([n:16]2[n:15][cH:14][cH:13][cH:17]2)[cH:9][c:8]([C:11]#[N:12])[c:6]([Cl:7])[cH:5]1

Participants

8

Reactant 2

HCID 1048PyrazoleHCID 1353971922-Chloro-4-ethoxy-5-iodobenzonitrile

Product 1

HCID 178466680HCID 178466680, compound

Reagents, catalysts & solvents 5

HCID 11430Potassium CarbonateReagentHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)CatalystHCID 75671341,10-phenanthroline-2,9-dicarboxylic AcidCatalystHCID 312751,4-DioxaneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
110 °C

Sources & evidence

ORD record
ord-df5f4d54d1304f1eac5e6db8b3398ecc
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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