(Triethylsilyl)acetylene → 5-Chloro-3-(triethyl-silanylethynyl)-pyrazin-2-ylamine
Reaction equation
[CH3:1][CH2:2][Si:3]([C:8]#[CH:9])([CH2:6][CH3:7])[CH2:4][CH3:5].[NH2:10][c:11]1[c:17](Br)[n:16][c:14]([Cl:15])[cH:13][n:12]1>>[CH3:1][CH2:2][Si:3]([C:8]#[C:9][c:17]1[c:11]([NH2:10])[n:12][cH:13][c:14]([Cl:15])[n:16]1)([CH2:6][CH3:7])[CH2:4][CH3:5]Participants
8
Reactant 2
Product 1
Reagents, catalysts & solvents 5
Conditions
- Temperature
- 25 °C
Sources & evidence
- ORD record
- ord-efe5f065205a4b878cacdf8d2bd8a5c0
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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