Hydrochloric Acid → 4-[(3-Bromophenyl)amino]-6-[(4-{N-[(ethoxycarbonyl)methyl]-N-methylamino}-1-oxo-2-buten-1-yl)-amino]-quinazoline
Reaction equation
[Br:10][c:11]1[cH:12][c:13]([NH:17][c:18]2[n:19][cH:20][n:21][c:22]3[cH:23][cH:24][c:25]([NH:28][C:29]([CH:30]=[CH:31][CH2:32][Br:33])=[O:34])[cH:26][c:27]23)[cH:14][cH:15][cH:16]1.[C:35](=[O:36])([O-:37])[OH:38].[CH2:2]([CH3:3])[O:4][C:5]([CH2:6][NH:7][CH3:8])=[O:9].[CH3:40][CH2:41][O:42][C:43](=[O:44])[CH3:45].[CH3:51][N:52]([CH3:53])[CH:54]=[O:55].[ClH:1].[Na+:39].[O:46]1[CH2:47][CH2:48][CH2:49][CH2:50]1>>[CH2:2]([CH3:3])[O:4][C:5]([CH2:6][N:7]([CH3:8])[CH2:32][CH:31]=[CH:30][C:29]([NH:28][c:25]1[cH:24][cH:23][c:22]2[n:21][cH:20][n:19][c:18]([NH:17][c:13]3[cH:12][c:11]([Br:10])[cH:16][cH:15][cH:14]3)[c:27]2[cH:26]1)=[O:34])=[O:9]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-813a64bece2b4d219a89b3cd0eea95b6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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