Acetate → Methyl 3-(4-amino-2-methylphenyl)prop-2-enoate

HRID 203350Notes

Reaction equation

HRID 203350 reaction equation
[Br:1][c:2]1[c:3]([CH3:9])[cH:4][c:5]([NH2:6])[cH:7][cH:8]1.[C:10]([CH:11]=[CH2:12])(=[O:13])[O:14][CH3:15].[C:46]([O-:47])(=[O:48])[CH3:49].[C:51]([O-:52])(=[O:53])[CH3:54].[CH3:16][c:17]1[cH:18][cH:19][cH:20][cH:21][c:22]1[P:23]([c:24]1[cH:25][cH:26][cH:27][cH:28][c:29]1[CH3:30])[c:31]1[cH:32][cH:33][cH:34][cH:35][c:36]1[CH3:37].[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[CH3:55][CH2:56][O:57][C:58](=[O:59])[CH3:60].[OH2:38].[Pd+2:50]>>[c:2]1([CH:12]=[CH:11][C:10](=[O:13])[O:14][CH3:15])[c:3]([CH3:9])[cH:4][c:5]([NH2:6])[cH:7][cH:8]1

Participants

9

Reactant 8

HCID 175Acetate2×HCID 962WaterHCID 7294Methyl AcrylateHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 233594-Bromo-3-methylanilineHCID 80271Tri-o-tolylphosphineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

Product 1

HCID 66876902Methyl 3-(4-amino-2-methylphenyl)prop-2-enoate

Sources & evidence

ORD record
ord-be815b27a35343d9b6264f50dc923542
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…