7H-Pyrrolo(2,3-d)pyrimidine, 4-chloro- → HCID 178525803, compound

HRID 2033963Notes

Reaction equation

HRID 2033963 reaction equation
[Cl:1][c:2]1[c:10]([c:6]2[n:5][cH:4][n:3]1)[cH:9][cH:8][nH:7]2.O[CH:11]1[C@H:34]([OH:35])[C@H:32]([OH:33])[C@@H:13]([C@@H:14]([c:24]2[cH:31][c:29]([F:30])[c:27]([Cl:28])[cH:26][cH:25]2)[O:15][C:16]([c:18]3[cH:23][cH:22][cH:21][cH:20][cH:19]3)=[O:17])[O:12]1>>[OH:33][C@@H:32]1[C@@H:13]([C@@H:14]([c:24]2[cH:31][c:29]([F:30])[c:27]([Cl:28])[cH:26][cH:25]2)[O:15][C:16]([c:18]3[cH:23][cH:22][cH:21][cH:20][cH:19]3)=[O:17])[O:12][CH:11]([n:7]4[c:6]([c:10]5[cH:9][cH:8]4)[n:5][cH:4][n:3][c:2]5[Cl:1])[C@@H:34]1[OH:35]

Participants

7

Reactant 2

HCID 53566827H-Pyrrolo(2,3-d)pyrimidine, 4-chloro-HCID 122482768HCID 122482768, compound

Product 1

HCID 178525803HCID 178525803, compound

Reagents, catalysts & solvents 4

HCID 13831TributylphosphineReagentHCID 5363146Diisopropyl azodicarboxylateReagentHCID 8028TetrahydrofuranSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
20 °C

Sources & evidence

ORD record
ord-a67274aaaa0e4dc3a42258fc3b1babbc
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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