Ammonia → HCID 178483214, compound

HRID 2058717Notes

Reaction equation

HRID 2058717 reaction equation
C(N=C(SC)NCCCOC1C=CC=C(CN2CCCCC2)C=1)#N.O.NN.[N:28]1([CH2:34][C:35]2[CH:36]=[C:37]([CH:49]=[CH:50][CH:51]=2)[O:38][CH2:39][CH2:40][CH2:41][N:42]2[C:46]([NH2:47])=[N:45][C:44]([NH2:48])=[N:43]2)[CH2:33]CCC[CH2:29]1.N>C(O)(C)C.O.C(OCC)(=O)C>[CH3:29][N:28]([CH2:34][C:35]1[CH:36]=[C:37]([CH:49]=[CH:50][CH:51]=1)[O:38][CH2:39][CH2:40][CH2:41][NH:42][C:46]1[NH:47][N:43]=[C:44]([NH2:48])[N:45]=1)[CH3:33]

Participants

8

Reactant 4

HCID 222AmmoniaHCID 24654Hydrazine hydrate (1:1)HCID 21297553HCID 21297553, compoundHCID 178503920HCID 178503920, compound

Product 1

HCID 178483214HCID 178483214, compound

Reagents, catalysts & solvents 3

HCID 962WaterSolventHCID 3776IsopropanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

Similarly prepared from N'-cyano-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-carbamimidothioic acid, methyl ester (14.1 g) and hydrazine hydrate (10 ml) was N3 -[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-1H-1,2,4-triazole-3,5-diamine (10.4 g) m.p. 100°-101.5°. TLC silica; ethyl acetate:water:isopropanol:0.088 ammonia 25:8:15:2; Rf 0.4.

Sources & evidence

ORD record
ord-5da490ec174a4253bc3a181250bb5cc7
Source dataset
uspto-grants-1982_03
Patent number
US04318913

Reaction notes

Loading…