Furfural → HCID 178477496, compound

HRID 2059392Notes

Reaction equation

HRID 2059392 reaction equation
O=Cc1ccco1.CCSC(=O)C(OCc1ccccc1)C(=O)O>C1CCNCC1.CN(C)c1ccncc1.C1CCOC1>CCSC(=O)/C(=C/c1ccco1)OCc1ccccc1

Participants

6

Reactant 2

HCID 7362FurfuralHCID 178477513HCID 178477513, compound

Product 1

HCID 178477496HCID 178477496, compoundYield 92%

Reagents, catalysts & solvents 3

HCID 142844-(Dimethylamino)pyridineReagentHCID 8082PiperidineCatalystHCID 8028TetrahydrofuranSolvent

Conditions

Temperature
25 °C

Workup

  1. temperatureThe product mixture was cooled to 25 °C.
  2. filtrationFiltered through a pad of celite · Keep Organic
  3. wash"The celite was washed with ethyl acetate (3 x 1 mL)."
  4. concentrationThe filtrate was concentrated under reduced pressure
  5. additionA 0.07 M stock solution of the internal standard ethylene carbonate (0.70 mL in CDCl3) was added.

Sources & evidence

ORD record
ord-fe172788025c4c20b91df38b05f746a1
Source dataset
Transfer learning optimization of 26 decarboxylative olefination reactions

Reaction notes

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