Tetrahydrofuran → Tert-butyl 3-[1-[2-(2-chlorophenyl)phenyl]-1-hydroxy-5-methoxypentyl]piperidine-1-carboxylate
Reaction equation
[C:10]([CH3:11])([CH3:12])([CH3:13])[O:14][C:15](=[O:16])[N:17]1[CH2:18][CH:19]([C:23]([c:24]2[c:25](-[c:30]3[c:31]([Cl:36])[cH:32][cH:33][cH:34][cH:35]3)[cH:26][cH:27][cH:28][cH:29]2)=[O:37])[CH2:20][CH2:21][CH2:22]1.[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[Cl:3][CH2:4][CH2:5][CH2:6][CH2:7][O:8][CH3:9].[I:2].[Mg:1]>>[CH2:4]([CH2:5][CH2:6][CH2:7][O:8][CH3:9])[C:23]([CH:19]1[CH2:18][N:17]([C:15]([O:14][C:10]([CH3:11])([CH3:12])[CH3:13])=[O:16])[CH2:22][CH2:21][CH2:20]1)([c:24]1[c:25](-[c:30]2[c:31]([Cl:36])[cH:32][cH:33][cH:34][cH:35]2)[cH:26][cH:27][cH:28][cH:29]1)[OH:37]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-cca634dbfb6b497191736da2c1307099
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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