Hydrochloric Acid → HCID 19096389, compound

HRID 2081719Notes

Reaction equation

HRID 2081719 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([CH:7]=O)=[CH:3][CH:2]=1.[CH3:9][C:10](=[O:15])[CH2:11][C:12](=[O:14])[CH3:13].[ClH:16]>CN(C)C=O>[ClH:16].[N:1]1[CH:2]=[CH:3][C:4]([CH:7]=[C:11]([C:10](=[O:15])[CH3:9])[C:12](=[O:14])[CH3:13])=[CH:5][CH:6]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 133894-PyridinecarboxaldehydeHCID 31261Acetylacetone

Product 1

HCID 19096389HCID 19096389, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
20 °C

Procedure

A solution containing 1.1 g of pyridine-4-carboxaldehyde and 1.0 g of 2,4-pentanedione in 10 ml of N,N-dimethylformamide was saturated with hydrogen chloride gas at 20° C. The solution was stirred for 1 h at 20° C. and then for 2 h at 80° C. The solvent was evaporated in vacuo and the residue was crystallized from ethanol. Yield 0.17 g, mp 175°-186° C.

Workup

  1. waitfor 2 h at 80° C
  2. customThe solvent was evaporated in vacuo
  3. customthe residue was crystallized from ethanol

Sources & evidence

ORD record
ord-e5a9ef2d4b6244e5882d511e275f39f2
Source dataset
uspto-grants-1993_02
Patent number
US05185370

Reaction notes

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