Dimethylformamide → N-[5-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)-2-fluorophenyl]-3-(2-methoxyethoxy)-1-methyl-1H-pyrazole-5-carboxamide
Reaction equation
[CH3:15][N:16]([CH3:17])[CH:18]=[O:19].[CH3:1][O:2][CH2:3][CH2:4][O:5][c:6]1[n:7][n:8]([CH3:14])[c:9]([C:11](=[O:12])[OH:13])[cH:10]1.[CH3:50][N:51]1[CH2:52][CH2:53][CH2:54][C:55]1=[O:56].[Cl:20][C:21]([C:22]([Cl:23])=[O:24])=[O:25].[NH2:26][c:27]1[cH:28][c:29]([O:30][c:31]2[cH:32][cH:33][c:34]3[n:35]([n:36]2)[cH:37][c:38]([NH:40][C:41](=[O:42])[CH:43]2[CH2:44][CH2:45]2)[n:39]3)[cH:46][cH:47][c:48]1[F:49].[O:57]1[CH2:58][CH2:59][CH2:60][CH2:61]1>>[CH3:1][O:2][CH2:3][CH2:4][O:5][c:6]1[n:7][n:8]([CH3:14])[c:9]([C:11](=[O:13])[NH:26][c:27]2[cH:28][c:29]([O:30][c:31]3[cH:32][cH:33][c:34]4[n:35]([n:36]3)[cH:37][c:38]([NH:40][C:41](=[O:42])[CH:43]3[CH2:44][CH2:45]3)[n:39]4)[cH:46][cH:47][c:48]2[F:49])[cH:10]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-fd976ffdd2504ea28771119b1bb4511b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…