HRID208659

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID1727

4-Aminopyridine

C5H6N2

HCID6344

Dichloromethane

CH2Cl2

HCID8471

Triethylamine

C6H15N

HCID14284

N,N-Dimethylpyridin-4-amine

C7H10N2

HCID65578

Ethanedioyl dichloride

C2Cl2O2

HCID59313818

未命名化合物

HCID59313908

未命名化合物

HCID59624671

6,8-Dichloro-N-(pyridin-4-yl)imidazo[1,2-b]pyridazine-3-carboxamide

C12H7Cl2N5O

PRODUCTS

生成物

HCID59624590

8-Bromo-6-chloro-N-(pyridin-4-yl)imidazo[1,2-b]pyridazine-3-carboxamide

C12H7BrClN5O

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f720defd83724c97bc2eae45f0618cff
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (6/10)

反应 SMILES

[Br:1][c:2]1[c:3]2[n:4]([n:5][c:6]([Cl:8])[cH:7]1)[c:9]([C:12](=[O:13])[OH:14])[cH:10][n:11]2.[CH3:35][CH2:36][N:37]([CH2:38][CH3:39])[CH2:40][CH3:41].[CH3:72][N:73]([c:74]1[cH:75][cH:76][n:77][cH:78][cH:79]1)[CH3:80].[Cl:15][c:16]1[cH:17][c:18]([Cl:19])[c:20]2[n:21]([c:22]([C:23]([OH:24])=[O:25])[cH:26][n:27]2)[n:28]1.[Cl:29][C:30]([C:31]([Cl:32])=[O:33])=[O:34].[Cl:49][c:50]1[cH:51][c:52]([Cl:53])[c:54]2[n:55]([c:56]([C:57]([NH:58][c:59]3[cH:60][cH:61][n:62][cH:63][cH:64]3)=[O:65])[cH:66][n:67]2)[n:68]1.[Cl:69][CH2:70][Cl:71].[NH2:42][c:43]1[cH:44][cH:45][n:46][cH:47][cH:48]1>>[Br:1][c:2]1[c:3]2[n:4]([n:5][c:6]([Cl:8])[cH:7]1)[c:9]([C:12](=[O:14])[NH:42][c:43]1[cH:44][cH:45][n:46][cH:47][cH:48]1)[cH:10][n:11]2