Acetate → Methyl 3-(1H-indol-7-yl)prop-2-enoate

HRID 209726Notes

Reaction equation

HRID 209726 reaction equation
[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[cH:7][cH:8][nH:9][c:10]12.[C:11]([CH:12]=[CH2:13])(=[O:14])[O:15][CH3:16].[CH3:54][N:55]([CH3:56])[CH:57]=[O:58].[CH:36]([N:37]([CH2:38][CH3:39])[CH:40]([CH3:41])[CH3:42])([CH3:43])[CH3:44].[O-:46][C:47]([CH3:48])=[O:49].[O-:50][C:51]([CH3:52])=[O:53].[Pd+2:45].[c:17]1([P:18]([c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[cH:31][cH:32][cH:33][cH:34][cH:35]1>>[c:2]1([CH:13]=[CH:12][C:11](=[O:14])[O:15][CH3:16])[cH:3][cH:4][cH:5][c:6]2[cH:7][cH:8][nH:9][c:10]12

Participants

8

Reactant 7

HCID 175Acetate2×HCID 6228DimethylformamideHCID 7294Methyl AcrylateHCID 11776TriphenylphosphineHCID 81531DiisopropylethylamineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 27570207-Bromoindole

Product 1

HCID 60150254Methyl 3-(1H-indol-7-yl)prop-2-enoate

Sources & evidence

ORD record
ord-d704871a1c224fec96f595d42b1caf97
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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