Dimethylformamide → N-(3-fluoro-4-(thieno[3,2-b]pyridin-7-yloxy)phenyl)-1-(4-fluorophenyl)-2-oxopyrrolidine-3-carboxamide
Reaction equation
[CH3:17][CH2:18][N:19]=[C:20]=[N:21][CH2:22][CH2:23][CH2:24][N:25]([CH3:26])[CH3:27].[CH3:56][CH2:57][N:58]([CH2:59][CH3:60])[CH2:61][CH3:62].[CH3:68][CH2:69][O:70][C:71]([CH3:72])=[O:73].[F:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[C:9](=[O:16])[CH:10]([C:13](=[O:14])[OH:15])[CH2:11][CH2:12]2)[cH:6][cH:7]1.[F:38][c:39]1[cH:40][c:41]([NH2:42])[cH:43][cH:44][c:45]1[O:46][c:47]1[c:48]2[c:49]([n:50][cH:51][cH:52]1)[cH:53][cH:54][s:55]2.[O:63]=[CH:64][N:65]([CH3:66])[CH3:67].[OH:28][n:29]1[c:30]2[c:31]([cH:32][cH:33][cH:34][cH:35]2)[n:36][n:37]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[C:9](=[O:16])[CH:10]([C:13](=[O:15])[NH:42][c:41]3[cH:40][c:39]([F:38])[c:45]([O:46][c:47]4[c:48]5[c:49]([n:50][cH:51][cH:52]4)[cH:53][cH:54][s:55]5)[cH:44][cH:43]3)[CH2:11][CH2:12]2)[cH:6][cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-362bd4ce7089490fa6883da48f34806e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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