反应详情

Potassium carbonate (0.76 g) and benzylbromide (0.94 g) were added to a solution of 1-allyl-4-chloro-1,3-dihydroimidazo[4.5-c]pyridin-2-one (1.05 g) in N,N-dimethylformamide (50 mL). This was stirred at room temperature for 14 hours. Water (300 mL) and ethyl acetate (300 mL) were added, and the organic layer was washed three times with 100 mL of water and then once with 100 mL of saturated aqueous sodium chloride solution, then was dried over magnesium sulfate, and concentrated under reduced pressure to give the title compound (1.57 g).

1. washthe organic layer was washed three times with 100 mL of water
2. dry with materialonce with 100 mL of saturated aqueous sodium chloride solution, then was dried over magnesium sulfate
3. concentrationconcentrated under reduced pressure