Tetrahydrofuran → HCID 67690736, compound

HRID 2122328Notes

Reaction equation

HRID 2122328 reaction equation
[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[Cu:43][I:44].[I:1][c:2]1[cH:3][c:4]([CH2:8][C:9](=[O:10])[NH:11][c:12]2[c:13]([C:14](=[O:15])[O:16][CH3:17])[cH:18][cH:19][c:20]([Cl:22])[cH:21]2)[cH:5][cH:6][cH:7]1.[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1.[Pd:45]([Cl:46])[Cl:47].[c:23]1([C:29]#[CH:30])[cH:24][cH:25][cH:26][cH:27][cH:28]1.[c:48]1([P:49]([c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[cH:62][cH:63][cH:64][cH:65][cH:66]1.[c:67]1([P:68]([c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)[c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)[cH:81][cH:82][cH:83][cH:84][cH:85]1>>[c:2]1([C:30]#[C:29][c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[cH:3][c:4]([CH2:8][C:9](=[O:10])[NH:11][c:12]2[c:13]([C:14](=[O:15])[O:16][CH3:17])[cH:18][cH:19][c:20]([Cl:22])[cH:21]2)[cH:5][cH:6][cH:7]1

Participants

8

Reactant 7

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 10821PhenylacetyleneHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 53966750HCID 53966750, compound

Product 1

HCID 67690736HCID 67690736, compound

Sources & evidence

ORD record
ord-3d5787a3437248ee97912655801fceb6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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