Bicarbonate Ion → 2-Chloro-3-(2,2,2-trifluoroethoxy)pyridine

HRID 2124377Notes

Reaction equation

HRID 2124377 reaction equation
[C:35](=[O:36])([OH:37])[O-:38].[Mg+2:22].[N:28]([O:29][C:30]([CH3:31])([CH3:32])[CH3:33])=[O:34].[NH2:1][c:2]1[c:3]([Cl:8])[n:4][cH:5][cH:6][cH:7]1.[Na+:39].[O-:23][S:24](=[O:25])(=[O:26])[O-:27].[OH:15][C:16]([C:17]([F:18])([F:19])[F:20])=[O:21].[OH:9][CH2:10][C:11]([F:12])([F:13])[F:14]>>[c:2]1([O:9][CH2:10][C:11]([F:12])([F:13])[F:14])[c:3]([Cl:8])[n:4][cH:5][cH:6][cH:7]1

Participants

9

Reactant 8

HCID 769Bicarbonate IonHCID 888Magnesium CationHCID 923Sodium ionHCID 1117Sulfate IonHCID 64092,2,2-TrifluoroethanolHCID 6422Trifluoroacetic acidHCID 10906Tert-Butyl nitriteHCID 805282-Chloro-3-pyridylamine

Product 1

HCID 120567282-Chloro-3-(2,2,2-trifluoroethoxy)pyridine

Sources & evidence

ORD record
ord-268f960663524889877df4455cfc92a2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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