N,N-Dimethylglycine → N-({4-chloro-3-[(3-chloro-5-cyanophenyl)oxy]-2-fluorophenyl}methyl)-5-[(N,N-dimethylglycyl)amino]-1H-indole-2-carboxamide
Reaction equation
[CH3:40][N:41]([CH3:42])[CH2:43][C:44]([OH:45])=[O:46].[CH3:61][CH2:62][O:63][C:64]([CH3:65])=[O:66].[CH:47]([N:48]([CH:49]([CH3:50])[CH3:51])[CH2:52][CH3:53])([CH3:54])[CH3:55].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[NH2:8][c:9]1[cH:10][c:11]2[cH:12][c:13]([C:18](=[O:19])[NH:20][CH2:21][c:22]3[c:23]([F:39])[c:24]([O:29][c:30]4[cH:31][c:32]([Cl:38])[cH:33][c:34]([C:36]#[N:37])[cH:35]4)[c:25]([Cl:28])[cH:26][cH:27]3)[nH:14][c:15]2[cH:16][cH:17]1.[O:56]=[CH:57][N:58]([CH3:59])[CH3:60].[OH2:67]>>[NH:8]([c:9]1[cH:10][c:11]2[cH:12][c:13]([C:18](=[O:19])[NH:20][CH2:21][c:22]3[c:23]([F:39])[c:24]([O:29][c:30]4[cH:31][c:32]([Cl:38])[cH:33][c:34]([C:36]#[N:37])[cH:35]4)[c:25]([Cl:28])[cH:26][cH:27]3)[nH:14][c:15]2[cH:16][cH:17]1)[C:44]([CH2:43][N:41]([CH3:40])[CH3:42])=[O:45]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-aa5f4ca63fb445049f0fc7298f9bb96a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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