4-Aminobenzoic Acid → 4-[N-(4-Nitrobenzyloxycarbonyl)glycylamino]-benzoic acid

HRID 212691Notes

Reaction equation

HRID 212691 reaction equation
[CH2:25]([NH+:26]([CH2:27][CH3:28])[CH2:29][CH3:30])[CH3:31].[CH3:45][CH2:46][O:47][C:48](=[O:49])[CH3:50].[CH3:51][CH2:52][CH2:53][CH2:54][CH2:55][CH3:56].[CH3:57][CH2:58][N:59]([CH2:60][CH3:61])[CH2:62][CH3:63].[CH3:64][N:65]([CH3:66])[CH:67]=[O:68].[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[Cl:42][CH2:43][Cl:44].[N+:7](=[O:8])([O-:9])[c:10]1[cH:11][cH:12][c:13]([CH2:14][O:15][C:16](=[O:17])[NH:18][CH2:19][C:20](=[O:21])[OH:22])[cH:23][cH:24]1.[NH2:32][c:33]1[cH:34][cH:35][c:36]([C:37](=[O:38])[OH:39])[cH:40][cH:41]1>>[N+:7](=[O:8])([O-:9])[c:10]1[cH:11][cH:12][c:13]([CH2:14][O:15][C:16](=[O:17])[NH:18][CH2:19][C:20](=[O:22])[NH:32][c:33]2[cH:34][cH:35][c:36]([C:37](=[O:38])[OH:39])[cH:40][cH:41]2)[cH:23][cH:24]1

Participants

10

Reactant 9

HCID 9784-Aminobenzoic AcidHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 8058HexaneHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 65578Oxalyl chlorideHCID 1385867TriethylammoniumHCID 12187147N-(p-nitrobenzyloxycarbonyl)glycine

Product 1

HCID 212489994-[N-(4-Nitrobenzyloxycarbonyl)glycylamino]-benzoic acid

Sources & evidence

ORD record
ord-37f920dff8fe4975bf48b74ba1b735ce
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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