1,2-Dichloroethane → 4-Bromo-1-cyclopropylpyridin-2(1H)-one

HRID 2129108Notes

Reaction equation

HRID 2129108 reaction equation
[Br:1][c:2]1[cH:3][c:4](=[O:8])[nH:5][cH:6][cH:7]1.[C:27](=[O:28])([O-:29])[O-:30].[C:35]([O-:36])(=[O:37])[CH3:38].[C:40]([O-:41])(=[O:42])[CH3:43].[CH:9]1([B:12]([OH:13])[OH:14])[CH2:10][CH2:11]1.[Cl-:33].[Cl:44][CH2:45][CH2:46][Cl:47].[Cu+2:39].[NH4+:34].[Na+:31].[Na+:32].[n:15]1[cH:16][cH:17][cH:18][cH:19][c:20]1-[c:21]1[cH:22][cH:23][cH:24][cH:25][n:26]1>>[Br:1][c:2]1[cH:3][c:4](=[O:8])[n:5]([CH:9]2[CH2:10][CH2:11]2)[cH:6][cH:7]1

Participants

11

Reactant 10

HCID 111,2-DichloroethaneHCID 175Acetate2×HCID 223AmmoniumHCID 312ChlorideHCID 923Sodium ion2×HCID 14742,2'-BipyridineHCID 19660Carbonate IonHCID 27099Cupric cationHCID 8171154-Bromo-2-hydroxypyridineHCID 2760897Cyclopropylboronic acid

Product 1

HCID 596356474-Bromo-1-cyclopropylpyridin-2(1H)-one

Sources & evidence

ORD record
ord-380043526deb464184ac8b804a1ba7ac
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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