Hydrochloric Acid → 4-fluoro-N-(3-hydroxycyclohexyl)-5-[4-(trifluoromethyl)phenyl]-1,2-oxazole-3-carboxamide
Reaction equation
[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[CH3:47][N:48]([CH3:49])[CH2:50][CH2:51][CH2:52][N:53]=[C:54]=[N:55][CH2:56][CH3:57].[ClH:46].[F:1][c:2]1[c:3]([C:17](=[O:18])[OH:19])[n:4][o:5][c:6]1-[c:7]1[cH:8][cH:9][c:10]([C:13]([F:14])([F:15])[F:16])[cH:11][cH:12]1.[NH2:20][CH:21]1[CH2:22][CH:23]([OH:27])[CH2:24][CH2:25][CH2:26]1.[O:58]1[CH2:59][CH2:60][CH2:61][CH2:62]1.[OH2:28].[OH:29][n:30]1[c:31]2[cH:32][cH:33][cH:34][cH:35][c:36]2[n:37][n:38]1>>[F:1][c:2]1[c:3]([C:17](=[O:19])[NH:20][CH:21]2[CH2:22][CH:23]([OH:27])[CH2:24][CH2:25][CH2:26]2)[n:4][o:5][c:6]1-[c:7]1[cH:8][cH:9][c:10]([C:13]([F:14])([F:15])[F:16])[cH:11][cH:12]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-c7b1f2d8d250491c8311d0f873899d92
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…